Détails de la réservation
- Le : 16 June 2017
- De : 11 h 30
- à : 12 h 30
- Salle : Amphi Centre Broca Nouvelle - Aquitaine
Détails de l'évènement
Séminaire - Vincent Van Waes
Laboratoire de Neurosciences Intégratives et Cliniques Université de Franche-Comté -
UFR Sciences et Techniques, Besançon
"Transcranial direct current stimulation (tDCS) to treat addiction-related behaviors: Insights from animal models"
Résumé
New technologies have recently demonstrated promise for the treatment of several psychiatric disorders, including addiction. Among these techniques, transcranial direct current stimulation (tDCS) is of particular interest. tDCS is a non-invasive brain stimulation method that modulates cortical excitability. The few existing clinical data show that tDCS applied to the left dorsolateral prefrontal cortexreduces craving for alcohol and psychostimulantsin regular users and/ordependent patients. However, there is no consensus yet for the use of tDCS in clinical practice. This is probably partly because the neurobiological mechanisms underlying tDCS effects are not clearly defined. To gain a better understanding of the mode of action of tDCS, we have developed and validatedthis technique in mice, in cooperation with a biotech company (DIXI medical, France). We have collected behavioral data confirming the beneficial effect of tDCS on addiction-related behavior in mice. Currently, we areexploringneurobiological mechanisms underlying these effects. This work should allow us to developan innovative and affordable clinicaltool to reduce craving for alcohol and other drugs of abuse, thereby facilitating drug consumption cessation in dependent patients.
Invitant : Muriel Darnaudéry, Professor of Neuroscience University Bordeaux lab NutriNeurO- UMR INRA 1286
Responsable
- Nom : DARNAUDERY Muriel