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Séminaier Fr transBioMed Chiswili Yves Chabu "Mechanisms of Cell-cell Interactions in Oncogenic Ras Tumors "

Détails de la réservation

Détails de l'évènement

Chiswili Yves Chabu

Cancer Research Center - University of Missoury


 
"Mechanisms of Cell-cell Interactions in Oncogenic Ras Tumors"

 

Résumé

In addition to genetic alterations, intercellular interactions in the tumor microenvironment significantly influence cancer progression in ways we don’t fully understand. Oncogenic Ras mutations give rise to aggressive cancers that are difficult to treat. While some of the underlying intracellular signals have been elucidated in exquisite details, much less is known about cell-cell interactions promoting Ras cancers. The characterization of these signals will broaden our cancer biology perspectives and potentially lead to novel targeted therapy strategies. Here I will discuss some of our ongoing efforts to delineate cell-cell signaling dynamics in the Ras tumor milieu using Drosophila and mouse tumor models.

Invitation : José-Eduardo Gomes – IBGC CNRS 5095

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Responsable

  • Nom : Rocher Virginie