Détails de la réservation
- Le : 19 January 2018
- De : 11 h 00
- à : 13 h 00
- Salle : Amphi Centre Broca Nouvelle - Aquitaine
Détails de l'évènement
Marie-Claude Potier
DR CNRS / ICM Paris
"Intellectual disabilities in Down syndrome from birth and throughout life: assessment and treatment"
Résumé
Down syndrome due to trisomy 21 (T21) is the leading genetic cause of mental retardation affecting more than 5 million people worldwide. Individuals carrying T21 show cognitive impairments of variable intensity from an early age and histopathological and clinical signs of Alzheimer's disease in their forties.
After the entire sequencing of chromosome 21 in 2000, the development of mouse models of Down syndrome and the study of expression of the three copies genes in a T21 context, current research focuses on treatment of cognitive deficits in children and young adults, and the prevention of dementia in elderly individuals by defining predictive biomarkers and new target-population.
Invitant : Maurice Garret, PhD, INCIA CNRS UMR 5287 / Université Bordeaux / Campus Carreire
Responsable
- Nom : Garret Maurice