Détails de la réservation
- Le : 10 September 2018
- De : 14 h 00
- à : 16 h 30
- Salle : Salle de conférence
Détails de l'évènement
Fabrice de Chaumont et Elodie Ey
Institut Pasteur
"Live Mouse Tracker: real-time behavioral analysis of groups of mice"
Résumé
Preclinical studies of psychiatric disorders require the use of animal models to investigate the impact of environmental factors or genetic mutations on complex traits such as decision-making and social interactions. Here, we present a real-time method for behavior analysis of mice housed in groups that couples computer vision, machine learning and Triggered-RFID identification to track and monitor animals over several days in enriched environments. The system extracts a thorough list of individual and collective behavioral traits and provides a unique phenotypic profile for each animal. On mouse models, we study the impact of mutations of genes Shank2 and Shank3 involved in autism. Characterization and integration of data from behavioral profiles of mutated female mice reveals distinctive activity levels and involvement in complex social configuration.
Invitant : Lisa Roux, Team Leader - Team Olfaction & Memory IINS UMR 5297 Centre Broca Nouvelle-Aquitaine
Responsable
- Nom : Lisa Roux